Background: Microelectrode arrays play an important role in prosthetic implants for\nneural signal recording or applying electrical pulses stimulation to target nerve system.\nSafety and long-term reliability are essential requirements for microelectrode arrays\napplied in electrical stimulation. In design and fabrication of the microelectrode array,\nsoft materials are generally chosen to be the substrate for the aim of achieving better\ncompliance with the surrounding tissue while maintaining minimal damage. By flexing\nof the array to the surface, the array is capable of keeping a more stable electrical\ncontact resulting in a significantly improved signal detected.\nMethods: In this study, we design and fabricate a flexible microelectrode array with\ngold as the electrode material and parylene-C as the substrate. The fabrication process\nof the array is presented. The in vitro electrochemical characteristics of the microelectrode\nare investigated by electrochemical impedance spectroscopy and cyclic voltammetry\nin a three-electrode electrochemical cell containing phosphate-buffered saline.\nCharge injection capacity measurements are carried out by multichannel systems and\nthe CSC of the microarray is calculated...............
Loading....